https://www.givemove.org/home daily 1.0 2022-08-05 https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585836036533-IQ736O8G0M02H0P3HOCH/564_Lesotho_Cascade_DSC1164_pixels.jpg Home - Assessing the clinical impact of HIV-1 genotypic resistance testing… GIVE MOVE will assess the influence of genotypic resistance testing on clinical decision making and its impact on the health of children and adolescents with unsuppressed HIV-1. https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1586855804214-PPMJ5A860N5OGYF11IGH/DSC02294_3_pix.jpeg Home - …and if clinically relevant, assessing the cost and cost-effectiveness of HIV-1 genotypic resistance testing. The cost and cost-effectiveness analysis, in combination with lessons learned with respect to feasibility, are intended to guide implementation of HIV-1 resistance testing in countries or settings were access is currently limited. https://www.givemove.org/project-overview daily 0.75 2024-06-10 https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585820604372-N4TDJ1IIKNBIQ7PDA9PZ/IMG_3863.jpeg Project Overview - The project in brief Scanning of plasma samples for viral load testing in Butha-Buthe, Lesotho. https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585893966055-N28KJAK9ZQ1O123U2MSM/project_countries.png Project Overview GIVE MOVE project countries and sites. https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1586855947864-2TSJP7SDI78MT331IVLE/DSC02555_2_pix3.jpg Project Overview Consenting procedure in Lesotho https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1586101739502-3LY88ZAYL0TYN3O9L3PZ/csm_CDCI_P1030303_20161123172207_35b024ad80.jpg Project Overview One-Stop Clinic in Ifakara, Tanzania https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585818264526-GZKOI4OL6ATFBLERY2YR/SwissTPH_logo.png Project Overview https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585818312145-KC4YE8GTUWQQCE2MNOUK/SolidarMed_logo.png Project Overview https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585818475580-92730MNL4BXB5ULTQPDD/BCMCF-L_logo.jpg Project Overview https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585818749998-JGN54KGVA2MWKLB7K1YI/5_OneStopClinic_logo.png Project Overview https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585818735342-LR6JTSRISFGB2SZFQ4PO/IHI_logo.png Project Overview https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585848698657-K6QM1MQBOPG5FL5JF5G5/USB_logo.png Project Overview https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585820097620-RTOCB4C3W0WPV7AHF4VF/SMH_logo.jpg Project Overview https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585818832312-AWF8BWOVZ75FONIXJ9F8/UniBas_logo.jpg Project Overview https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/c43de2f2-3aa5-4082-8df0-3b028464cac2/MDH_logo.png Project Overview - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585818864143-38RQYV84YX74O1W6JLTA/DBM_logo.png Project Overview https://www.givemove.org/team daily 0.75 2023-11-28 https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585812562101-ZNBT3QX0W2EVG1SSS60M/LabhardtN.jpg Team Niklaus Labhardt, Sponsor / Chief Investigator https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585812586043-V16X0ZDRKYFSQTH6QQWQ/BrownJ.jpg Team Jennifer Brown, Principal Investigator https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585812624950-NO79DFHK6VO2JTMI0RK2/MuhairweJ.jpg Team Josephine Muhairwe, Clinical Advisor https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1586413908285-KIXNSIX8WUIKT3Y5L7SV/KayembeB.jpg Team Buntshi Paulin Kayembe, Clinical Coordinator BCMCFL https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1586412520138-MZ6SLQ7CMVFI25OSDT9G/6_HlasoaMM.jpg Team Mosa Molapo Hlasoa, Clinical Coordinator BCMCFL https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/25947e21-d057-4e12-9248-b3b470f1ae76/7b_RingeraI.jpg Team Isaac Ringera, Study Manager https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585812782553-W52CA8JA32GJ0OMB7TNX/WeisserM.jpg Team Maja Weisser, Clinical Coordinator CDCI https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585812804497-DRX097H9MJW13YVYOFTR/LuogaE.jpg Team Ezekiel Luoga, Ifakara Local Principal Investigator https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585812608988-VDJ99U7XE1YIE1ZU6IUO/KlimkaitT.jpg Team Thomas Klimkait, Expert Virology & Diagnostics https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1586352477727-P2MZ0EG3ENL6XUCMQBVD/GlassT.jpg Team Tracy Glass, Trial Statistician https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585774814830-NRMSVFEF6QSQA9357R8U/TeamLeribe.JPG Team Site team in Leribe, Lesotho: From left to right: ‘Me Moliehi Pii (Study nurse), ‘Me Palesa Mothibeli (Study Nurse), Dr Kaleu Claude Sambayi (former Local Principal Investigator). Not pictured: Dr Thomas Mbaya (Local Principal Investigator), ‘Me Mamonyake Mokete (Deputy Local Principal Investigator). https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1591605981027-RS4OFVPOIWAA8F6HX247/2b_ButhaButhe.jpeg Team Site team in Butha-Buthe, Lesotho: From left to right: Dr Masengo Lorraine Kabundi (Local Principal Investigator), ‘Me ‘Matšiu Ralitapole (Deputy Local Principal Investigator), ‘Me Mamello Lebitsa (Study Nurse) https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585774916650-QK0I14NQGBYYFBII00T8/TeamMokhotlong.JPG Team Site team in Mokhotlong, Lesotho: From left to right: ‘Me Mamotebang Malapane (Former Deputy Local Principal Investigator), ‘Me Makeletso Nkune (Local Principal Investigator). Not pictured: ‘Me Mamonyane Thite Makhalemele (Deputy Local Principal Investigator), ‘Me 'Matheo Philadel Ndaule, (Study Assistant), Dr Ching Wey David Yav (Former Local Principal Investigator), Blaise Lukau (Physician). https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1586354803644-T98EBXC8RWKDG82GQ8IP/Ifakara.png Team Site team in Ifakara, Tanzania: From left to right: Dr Ezekiel Luoga (Local Principal Investigator), Jenifa Tarimo (Study Nurse), Dr Getrud Joseph Mollel (Deputy Local Principal Investigator) https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1606984461451-0U96CHAV1TF3VEYMU568/maseru_team.jpg Team Site team in Maseru, Lesotho: Back: Dr Andreas Boy Isaac (Local Principal Investigator). Front, from left to right: ‘Me Mabatloung Moshabesha (Study Nurse), ‘Me Mamakoloane Ramochele (Study Nurse), ‘Me Esther Makhalanyane (Deputy Local Principal Investigator). https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1615981701839-D9OI3H7KZBON3ACKQFP6/seboche_team3.jpg Team Site team in Seboche, Lesotho: From left to right: ‘Me Kuena Mokhele (Local Principal Investigator), ‘Me Matseliso Setoko (Deputy Local Principal Investigator). https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1615461589632-GGLJAQW96E8NN06731NE/7_MHK.jpg Team Site team in Mohale’s Hoek, Lesotho: From left to right: Ntate Tjoloba Tjoloba (Deputy Local Principal Investigator), ‘Me Sebasi Makoae (Study Nurse), Dr Mulume Ilunga (Local Principal Investigator). https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/ce5e01b7-f7c9-47f2-88e1-f022a8d6101f/ThahaneL.jpg Team Lineo Thahane - Expert Paediatrics and HIV https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/39bf48b2-a800-48d2-ad49-4b0dd2ac0c18/David+Sando.jpg Team - Make it stand out David Sando - Clinical Expert https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/e02f2b6d-c852-479d-8867-8b33ecb04583/Kasasi+Mayogu.jpg Team - Make it stand out Kasasi Mayogu - Local Co-PI Dar es Salaam https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/a0bfc67d-e17e-4250-860d-ff1e4cffbd70/WhatsApp+Image+2023-11-20+at+17.30.28.jpg Team - Make it stand out Brenda Simba - Local Co-PI Dar es Salaam https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/7eca515d-ccde-464b-a2f5-fb2ff4d320c4/AmstutzA.jpg Team Alain Amstutz - Expert Clinical HIV https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/44e9c572-4511-4975-ba40-a02bd89ceee9/BresserM.jpg Team Moniek Bresser - Principal Data Manager https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/b0b4fb7e-a7a3-48e1-973f-78fdc9c377e8/BachmannN.jpg Team Nadine Tschumi - Expert Biostatistics and Data https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/79903a52-9e0c-4887-a968-1c70588f4349/MothobiB.jpg Team Buoang Mothobi - Quality Assurance Officer https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/d774fe92-2418-49cf-b113-1949c5f2a1f8/1_MolatelleM.jpg Team Mamello Molatelle - Head of GRT Laboratory Lesotho https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/4cbb99f8-db35-4f7e-bcbd-82e04ac15928/2_BelempiR.jpg Team Relebohile Belempi - GRT Laboratory Technologist Lesotho https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/89dff150-7848-4c0e-a81f-36753396e3e7/3_KimeraN.jpg Team Namvua Kimera - Responsible GRT Technologist Ifakara, Tanzania https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/8bd8ddf6-84a2-43c1-bc60-6a5a7fc4e47d/David+Temba+.jpg Team - Make it stand out David Temba - Responsible GRT Technologist Dar es Salaam sites, Tanzania https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/3d25efe1-8c0a-4a4e-854d-82c8c14f981a/person_icon.png Team - Make it stand out Theofrida Tembo - Laboratory Technologist Dar es Salaam sites, Tanzania https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/00a49025-8389-4015-af64-ff5bcf05b75a/person_icon.png Team - Make it stand out William Wedson - Laboratory Technologist Dar es Salaam sites, Tanzania https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585821549470-DMKZCUNOKC849ZLTFLWW/SwissTPH_logo.png Team https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585821909632-SQQXHTZDA379FFELU4EI/SolidarMed_logo.png Team https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585821929488-Z51XIPUBI9XRHPES4S71/BCMCF-L_logo.jpg Team https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585821974596-NNIDH1G4UEFV1JCXVLD2/OneStopClinic_logo.png Team https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585822019994-DG0B2DZI0Q2ZKCVXTI7N/IHI_logo.png Team https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585848434496-AM4CDFYZ20LLFVI53CUU/USB_logo.png Team https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585822046279-MZMGN09DCDZRHOZAAQUA/SMH_logo.jpg Team https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585822068858-UHVU66M3K4B3LURDL6MQ/UniBas_logo.jpg Team https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/a1065c90-b6d7-414d-8bda-9d9b489e990f/MDH_logo.png Team - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585822088367-HHW217PXU1V0KTFCCB28/DBM_logo.png Team https://www.givemove.org/news daily 0.75 2026-03-09 https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/f0eed33f-e6d4-4144-bd5c-41e3f294bfbe/GMres.JPG News - 07.03.2026 - Publication of nested results on resistance in the Journal of Antimicrobial Chemotherapy We report resistance-associated mutations and resistance levels from both study arms (post-hoc for the usual care arm), including longitudinal data where available. While substantial resistance was observed, including one case of dolutegravir resistance, most participants had three fully active drugs in their regimen. These findings further highlight the need for both better adherence interventions and more targeted approaches to resistance testing. doi: 10.1093/jac/dkag070. https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/268f0a1f-9f4b-4e83-8723-7a4cecaac403/presentation_glasgow_ed2.jpg News - 10-13.11.2024 - Secondary resistance findings presented at HIV Glasgow Christof Schönenberger represented the GIVE MOVE team presenting in-depth resistance findings, including post-hoc resistance testing for the control arm, at HIV Glasgow. https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/713b58ec-9405-48b6-bfb2-ab76aa98612a/GM_LancetGlobHealth_header.png News - 17.07.2024 - Publication of main findings in The Lancet Global Health The main trial results are out! Genotypic resistance testing-informed clinical management did not significantly improve treatment outcomes over standard care for children and adolescents with viraemia while taking antiretroviral therapy. doi: 10.1016/S2214-109X(24)00183-9. https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/936b489b-8f20-4fd0-bd97-3403a69abdd1/GM_croi.jpg News - 06.03.2024 - Primary results presented at CROI 2024 GIVE MOVE results were presented at the Conference on Retroviruses and Opportunistic Infections (CROI) 2024 and are available in the CROI webcast. https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/f8802e7d-39dd-4702-821f-24657e23f8ae/Dar_sites_training.jpg News - 12.04.2022 - Activation of three new sites in Tanzania Three MDH-supported sites in Dar es Salaam - Temeke Regional Referral Hospital, Mbagala Rangi Tatu Hospital, and Upendano Dispensary - are activated. Image: Training of Dar es Salaam site teams. https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1615981485335-UIEU3RMX3QIPHGEQH0P0/seboche.jpg News - 30.11.-03.12.2020 - Activation of two new sites in Lesotho The Seboche Mission Hospital (30.11.2020) and Baylor Maseru (03.12.2020) sites are formally activated. https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1599854523003-JRWOKR3EUUV0BPUVHYN9/Ifakara_01_ed2.jpg News - 29.07.2020 - Site activation in Ifakara, Tanzania Recruitment begins in Ifakara, Tanzania. Image: Data collection during an enrolment visit in Ifakara. https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585851333827-SEF8KCMZGF23J1KT6XDK/IMG_0274_4.jpeg News - 20.02.-09.03.2020 - Site activations in Lesotho The sites in Lesotho, the Baylor clinics in Leribe (20.02.2020), Butha-Buthe (27.02.2020) and Mokhotlong (09.03.2020), are formally activated. Image: Site Initiation Visit in Butha-Buthe. https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585850692010-4IM20OT4MB63U7NL9LQ8/DSC04025_3.jpeg News - 17.-18.01.2020 - GIVE MOVE training The Local Principal Investigators and Deputy Local Principal Investigators of the first three sites in Lesotho (Leribe, Butha-Buthe, Mokhotlong) get together for a two-day training on study procedures, using the study database (MACRO by Elsevier), correct study documentation, refresher of Good Clinical Practice principles, study documentation, quality assurance and monitoring, consenting procedures. https://www.givemove.org/funding daily 0.75 2024-08-27 https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585846518206-238UWSW9P9RLHC5E3XEK/Botnar_Logo.png Funding https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/1585846556692-C47C6OPG5MS2V15742SD/SNSF_Logo.png Funding https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/54fd1851-2cde-4516-ac37-c7ff06c5417a/bangerter_rhyner_logo.jpg Funding - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.givemove.org/scientific-information daily 0.75 2026-03-09 https://images.squarespace-cdn.com/content/v1/5e29a6a07745d3135476f6a0/72d136c7-4111-4fff-8175-3c5b0ef65c68/flowchart.png Scientific Information - Build it. Overview of GIVE MOVE treatment algorithm and study visits. The decision follow-up visit, occurring 6 months after the decision visit, is not shown. Further visits may be indicated and will be documented. ART: antiretroviral therapy; EAC: enhanced adherence counselling; GRT: genotypic resistance testing; VL: viral load. https://www.givemove.org/contact daily 0.75 2022-08-05